GL1X · GenesisL1 explorer

Ligand · V0K

V0K · 1-[[3,4-bis(fluoranyl)phenyl]methyl]-~{N}-[(1~{R})-2-[[(3~{E})-3-(1~{H}-imidazol-5-ylmethylidene)-2-oxidanylidene-1~{H}-indol-5-yl]amino]-2-oxidanylidene-1-phenyl-ethyl]-6-methyl-2-oxidanylidene-pyridine-3-carboxamide

V0K, 1-[[3,4-bis(fluoranyl)phenyl]methyl]-~{N}-[(1~{R})-2-[[(3~{E})-3-(1~{H}-imidazol-5-ylmethylidene)-2-oxidanylidene-1~{H}-indol-5-yl]amino]-2-oxidanylidene-1-phenyl-ethyl]-6-methyl-2-oxidanylidene-pyridine-3-carboxamide (C34 H26 F2 N6…

Component
V0K
Formula
C34 H26 F2 N6 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

V0K in 2 structures; the first of them:

  • 7O2V · Aurora kinase a in complex with the aur-A/PDK1 inhibitor VI8 · V0K A501 · binds ARG137, LEU139, GLY140, LYS141, GLY142, LYS143, GLY145, ASN146 and 18 more
  • 7O2V · Aurora kinase a in complex with the aur-A/PDK1 inhibitor VI8 · V0K A501 · binds ARG137, LEU139, GLY140, LYS141, GLY142, LYS143, GLY145, ASN146 and 18 more

Residues it binds most

GLY 2, LYS 2, LEU 2, ALA 2, ARG 2, ASN 2, GLU 2, CYS 2, PHE 2, PRO 2 (residue and the binding sites it lines).

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