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Ligand · UZH

UZH · 4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]-3-fluoranyl-phenyl]-9-[6-(methylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one

UZH, 4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]-3-fluoranyl-phenyl]-9-[6-(methylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one (C27 H38 F N7 O, 495.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
UZH
Formula
C27 H38 F N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

UZH in 2 structures; the first of them:

  • 7O2E · Crystal structure of the human METTL3-METTL14 complex bound to Compound 21 (ADO_AD_089) · UZH A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 14 more
  • 7O2E · Crystal structure of the human METTL3-METTL14 complex bound to compound 21 (ADO_AD_089) · UZH A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 11 more

Residues it binds most

GLY 2, ARG 2, ASP 2, PRO 2, ASN 2, CYS 2, GLN 2, GLU 2, ILE 2, LEU 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

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