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Ligand · UZ4

UZ4 · (2R,3S)-3-amino-2-hydroxy-4-[(3S)-2-oxopyrrolidin-3-yl]butanoic acid

UZ4, (2R,3S)-3-amino-2-hydroxy-4-[(3S)-2-oxopyrrolidin-3-yl]butanoic acid (C8 H14 N2 O4, 202.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
UZ4
Formula
C8 H14 N2 O4
Class
ligand
Structures
2
PDB entries
2

Binding sites

UZ4 in 2 structures; the first of them:

  • 6XBG · Crystal structure of the SARS-cov-2 (COVID-19) main protease in complex with inhibitor… · UZ4 C3 · binds HIS41, PHE140, LEU141, ASN142, GLY143, SER144, CYS145, HIS163 and 4 more
  • 6XBI · Crystal structure of the SARS-cov-2 (COVID-19) main protease in complex with inhibitor… · UZ4 D4 · binds HIS41, PHE140, ASN142, GLY143, SER144, CYS145, HIS163, HIS164 and 4 more

Residues it binds most

HIS 4, LEU 4, ASN 4, CYS 4, GLU 4, GLY 4, PHE 4, SER 4 (residue and the binding sites it lines).

Found with

  • UZ1 · Cyclopropanamine
  • NA · Sodium ion
  • GOL · Glycerol
  • P6S · benzyl hydrogen carbonate
  • UZ7 · Phenyl hydrogen carbonate
  • DMS · Dimethyl sulfoxide

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