GL1X · GenesisL1 explorer

Ligand · UPC

UPC · 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]uridine

UPC, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]uridine (C10 H17 N2 O13 P3, 466.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its…

Component
UPC
Formula
C10 H17 N2 O13 P3
Class
ligand
Structures
6
PDB entries
3

Binding sites

UPC in 6 structures; the first of them:

  • 3SPY · RB69 DNA Polymerase(L415A/L561A/S565G/Y567A) Ternary Complex with dUpCpp Opposite dA · UPC A902 · binds ASP411, LEU412, THR413, SER414, ALA415, TYR416, PRO417, ARG482 and 8 more
  • 3SPZ · DNA Polymerase(L415A/L561A/S565G/Y567A) Ternary Complex with dUpCpp Opposite dA (Ca2+) · UPC A904 · binds ASP411, LEU412, THR413, SER414, ALA415, TYR416, PRO417, ARG482 and 8 more
  • 4M28 · UDP-Glucose Pyrophosphorylase from Leishmania major in complex with UTP analog dUpCpp · UPC A1001 · binds LEU81, ASN82, GLY83, GLY84, LEU85, GLY86, THR87, LYS95 and 6 more
  • 3SPY · RB69 DNA POLYMERASE(L415A/L561A/S565G/Y567A) ternary complex with dupcpp opposite da · UPC A902 · binds ASP411, LEU412, THR413, SER414, ALA415, TYR416, PRO417, ARG482 and 8 more
  • 3SPZ · DNA POLYMERASE(L415A/L561A/S565G/Y567A) ternary complex with dupcpp opposite da (CA2+) · UPC A904 · binds ASP411, LEU412, THR413, SER414, ALA415, TYR416, PRO417, ARG482 and 8 more
  • 4M28 · Udp-glucose pyrophosphorylase from leishmania major in complex with UTP analog dupcpp · UPC A1001 · binds LEU81, ASN82, GLY83, GLY84, LEU85, GLY86, THR87, LYS95 and 6 more

Residues it binds most

ASP 6, LYS 6, THR 6, ASN 6, GLY 2, LEU 6, ALA 4, ARG 4, DA 4, DC 4 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • MG · Magnesium ion

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