GL1X · GenesisL1 explorer

Ligand · UMA

UMA · Uridine-5'-diphosphate-N-acetylmuramoyl-L-alanine

UMA, Uridine-5'-diphosphate-N-acetylmuramoyl-L-alanine (C23 H36 N4 O20 P2, 750.5 g/mol), in the MolNFT structures on GenesisL1: bound in 13 records (12 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
UMA
Formula
C23 H36 N4 O20 P2
Class
ligand
Structures
13
PDB entries
12

Binding sites

UMA in 13 structures; the first of them:

  • 1EEH · Udp-N-acetylmuramoyl-L-ALANINE:D-glutamate ligase · UMA A450 · binds ILE11, GLY12, GLY14, LEU15, THR16, GLY17, ASP35, THR36 and 14 more
  • 1P3D · Crystal Structure of UDP-N-acetylmuramic acid:L-alanine ligase (MurC) in Complex with UMA… · UMA A602 · binds GLY25, GLY27, GLY28, ALA29, GLY30, MSE31, SER48, ASP49 and 20 more
  • 1UAG · Udp-N-acetylmuramoyl-L-ALANINE:D-glutamate ligase · UMA A963 · binds ILE11, GLY12, GLY14, LEU15, THR16, ASP35, THR36, ARG37 and 18 more
  • 2JFG · Crystal structure of MurD ligase in complex with UMA and ADP · UMA A1440 · binds ILE11, GLY12, GLY14, LEU15, THR16, ASP35, THR36, ARG37 and 18 more
  • 2JFN · Crystal structure of Escherichia coli glutamate racemase in complex with L- Glutamate and… · UMA A1286 · binds LEU100, ARG104, VAL112, GLY113, VAL114, VAL115, PRO116, ALA117 and 9 more
  • 2UAG · Udp-N-acetylmuramoyl-L-ALANINE:D-glutamate ligase · UMA A450 · binds ILE11, GLY12, GLY14, LEU15, THR16, ASP35, THR36, ARG37 and 14 more
  • 3UAG · Udp-N-acetylmuramoyl-L-ALANINE:D-glutamate ligase · UMA A450 · binds ILE11, GLY12, GLY14, LEU15, THR16, ASP35, THR36, ARG37 and 17 more
  • 5A5F · Crystal structure of murd ligase from escherichia COLI in complex with uma and ADP · UMA A450 · binds ILE11, GLY12, GLY14, LEU15, THR16, ASP35, THR36, ARG37 and 16 more
  • 8DP2 · Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from… · UMA A501 · binds GLY14, GLY16, LYS17, SER18, ASP37, THR38, ARG39, SER76 and 10 more
  • 9BN8 · Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli… · UMA A501 · binds ILE11, GLY12, GLY14, LEU15, THR16, ASP35, THR36, ARG37 and 17 more
  • 9BN9 · Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli… · UMA A501 · binds ILE11, GLY12, GLY14, LEU15, THR16, ASP35, THR36, ARG37 and 17 more
  • 9DQW · Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli… · UMA A502 · binds ILE11, GLY12, GLY14, LEU15, THR16, ASP35, THR36, ARG37 and 16 more
  • 8DP2 · Crystal structure of udp-N-acetylmuramoylalanine--D-glutamate ligase (murd) from… · UMA A501 · binds GLY14, GLY16, LYS17, SER18, ASP37, THR38, ARG39, SER76 and 10 more

Residues it binds most

GLY 14, SER 14, ILE 12, ASP 13, LEU 12, PRO 12, ARG 14, THR 11, HIS 13, PHE 12 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • GOL · Glycerol
  • ADP · Adenosine-5'-diphosphate
  • MG · Magnesium ion
  • A1AQS · N-(4-{[(4S)-3-amino[1,2,4]triazolo[4,3-b]pyridazin-6-yl]sulfanyl}phenyl)acetamide
  • ANP · Phosphoaminophosphonic acid-adenylate ester
  • MN · Manganese (II) ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • ACT · Acetate ion
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
  • PE8 · 3,6,9,12,15,18,21-heptaoxatricosane-1,23-diol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.