GL1X · GenesisL1 explorer

Ligand · TP8

TP8 · 5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2-[(1Z)-1-hydroxy-3-(phosphonooxy)prop-1-en-1-yl]-3-{[(4Z)-4-imino-2- methyl-4,5-dihydropyrimidin-5-yl]methyl}-4-methyl-1,3-thiazol-3-ium

TP8, 5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2-[(1Z)-1-hydroxy-3-(phosphonooxy)prop-1-en-1-yl]-3-{[(4Z)-4-imino-2- methyl-4,5-dihydropyrimidin-5-yl]methyl}-4-methyl-1,3-thiazol-3-ium (C15 H21 N4 O12 P3 S -2, 574.3 g/mol), in the…

Component
TP8
Formula
C15 H21 N4 O12 P3 S -2
Class
ligand
Structures
2
PDB entries
1

Binding sites

TP8 in 2 structures; the first of them:

  • 2IHU · Carboxyethylarginine synthase from Streptomyces clavuligerus: putative reaction… · TP8 C600 · binds ILE410, GLY411, PHE412, PHE413, ARG414, SER436, SER437, PHE438 and 23 more
  • 2IHU · Carboxyethylarginine synthase from streptomyces clavuligerus: putative reaction… · TP8 C600 · binds ILE410, GLY411, PHE412, PHE413, ARG414, SER436, SER437, PHE438 and 23 more

Residues it binds most

GLY 2, ASN 2, PHE 2, ARG 2, ILE 2, SER 2, THR 2, TYR 2, VAL 2, ASP 2 (residue and the binding sites it lines).

Found with

  • TP9 · (3Z)-4-{[(4-amino-2-methylpyrimidin-5-yl)methyl]amino}-3-mercaptopent-3-en-1-yl trihydrogen diphosphate
  • K · Potassium ion
  • MG · Magnesium ion
  • GOL · Glycerol
  • TAR · D(-)-tartaric acid

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