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Ligand · TMG

TMG · 2-(1,3-thiazol-4-yl)-1H-benzimidazole

TMG, 2-(1,3-thiazol-4-yl)-1H-benzimidazole (C10 H7 N3 S, 201.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
TMG
Formula
C10 H7 N3 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

TMG in 4 structures; the first of them:

  • 1YVM · E. coli Methionine Aminopeptidase in complex with thiabendazole · TMG A501 · binds CYS59, TYR62, TYR65, CYS70, HIS79, TYR168, HIS178, TRP221
  • 3SFE · crystal structure of porcine mitochondrial respiratory complex II bound with oxaloacetate… · TMG C1 · binds PRO169, TRP173, HIS216, ILE218, ILE30, TRP35, MET39, SER42 and 3 more
  • 1YVM · E. COLI methionine aminopeptidase in complex with thiabendazole · TMG A501 · binds CYS59, TYR62, TYR65, CYS70, HIS79, TYR168, HIS178, TRP221
  • 3SFE · Crystal structure of porcine mitochondrial respiratory complex II bound with oxaloacetate… · TMG C1 · binds PRO169, TRP173, HIS216, ILE218, ILE30, TRP35, MET39, SER42 and 3 more

Residues it binds most

TYR 4, HIS 4, ILE 2, TRP 4, CYS 2, ARG 2, MET 2, PRO 2, SER 2 (residue and the binding sites it lines).

Found with

  • F3S · FE3-S4 cluster
  • FAD · Flavin-adenine dinucleotide
  • FES · Fe2/s2 (inorganic) cluster
  • HEM · Protoporphyrin IX containing Fe
  • OAA · Oxaloacetate ion
  • SF4 · Iron/sulfur cluster
  • CO · Cobalt (II) ion
  • NA · Sodium ion

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