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Ligand · TLP

TLP · 3-hydroxy-2-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl)-amino]-butyric acid

TLP, 3-hydroxy-2-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl)-amino]-butyric acid (C12 H19 N2 O8 P, 350.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
TLP
Formula
C12 H19 N2 O8 P
Class
ligand
Structures
2
PDB entries
1

Binding sites

TLP in 2 structures; the first of them:

  • 1LW4 · X-ray structure of L-Threonine Aldolase (low-specificity) in complex with L-allo-threonine · TLP B1050 · binds SER6, THR8, SER57, GLY58, THR59, ASN62, HIS83, TYR87 and 13 more
  • 1LW4 · X-ray structure of L-threonine aldolase (low-specificity) in complex with L-allo-threonine · TLP B1050 · binds SER6, THR8, SER57, GLY58, THR59, ASN62, HIS83, TYR87 and 13 more

Residues it binds most

ARG 6, SER 6, ASN 6, GLU 6, HIS 6, THR 6, ALA 6, ASP 6, CYS 6, GLY 6 (residue and the binding sites it lines).

Found with

  • PLP · Pyridoxal-5'-phosphate
  • CA · Calcium ion
  • CL · Chloride ion

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