GL1X · GenesisL1 explorer

Ligand · TLO

TLO · 5'-O-[(S)-hydroxy{[(s)-hydroxy(phenoxy) phosphoryl]oxy}phosphoryl]thymidine

TLO, 5'-O-[(S)-hydroxy{[(s)-hydroxy(phenoxy) phosphoryl]oxy}phosphoryl]thymidine (C16 H20 N2 O11 P2, 478.3 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (3 PDB entries). Every binding site with its residues within 4.5…

Component
TLO
Formula
C16 H20 N2 O11 P2
Class
ligand
Structures
5
PDB entries
3

Binding sites

TLO in 5 structures; the first of them:

  • 6M81 · Crystal structure of TylM1 Y14F bound to SAH and dTDP-phenol · TLO A302 · binds HIS26, LYS29, PHE118, SER119, HIS123, TRP152, TRP153, ASN157 and 11 more
  • 6M82 · Crystal structure of TylM1 Y14paF bound to SAH and dTDP-phenol · TLO A302 · binds HIS26, LYS29, PHE118, TRP152, TRP153, ASN157, PHE158, THR159 and 8 more
  • 6M81 · Crystal structure of TYLM1 Y14F bound to sah and dtdp-phenol · TLO A302 · binds LYS29, PHE118, HIS123, TRP152, TRP153, ASN157, PHE158, THR159 and 9 more
  • 6M82 · Crystal structure of TYLM1 Y14PAF bound to sah and dtdp-phenol · TLO A302 · binds HIS26, LYS29, PHE118, TRP152, TRP153, ASN157, PHE158, THR159 and 8 more
  • 6M83 · Crystal structure of TYLM1 S120A bound to sah and dtdp-phenol · TLO A302 · binds TYR14, HIS26, LYS29, PHE118, TRP152, TRP153, ASN157, PHE158 and 9 more

Residues it binds most

SER 11, ARG 11, PHE 11, TRP 11, THR 11, HIS 10, ILE 9, TYR 11, ALA 11, ASN 11 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • SAH · S-adenosyl-L-homocysteine
  • CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.