GL1X · GenesisL1 explorer

Ligand · TGF

TGF · 2-[4-(4-{4-[(2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydro-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-carboxy-butyrylam ino)-4-carboxy-butyrylamino]-pentanedioic acid

TGF, 2-[4-(4-{4-[(2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydro-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-carboxy-butyrylam ino)-4-carboxy-butyrylamino]-pentanedioic acid (C30 H37 N9 O13, 731.7 g/mol), in the MolNFT structures on…

Component
TGF
Formula
C30 H37 N9 O13
Class
ligand
Structures
2
PDB entries
1

Binding sites

TGF in 2 structures; the first of them:

  • 1LS3 · Crystal Structure of the Complex between Rabbit Cytosolic Serine Hydroxymethyltransferase… · TGF B420C · binds GLU57, TYR64, TYR65, PHE257, PRO258, LEU121, GLY124, GLY125 and 10 more
  • 1LS3 · Crystal structure of the complex between rabbit cytosolic serine hydroxymethyltransferase… · TGF B420C · binds GLU57, TYR64, TYR65, PHE257, PRO258, LEU121, GLY124, GLY125 and 10 more

Residues it binds most

LEU 4, GLY 4, TYR 4, ARG 4, ASN 4, PRO 4, CYS 4, GLU 4, HIS 4, ILE 4 (residue and the binding sites it lines).

Found with

  • GLY · Glycine
  • PLP · Pyridoxal-5'-phosphate
  • GOL · Glycerol

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