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Ligand · TG

TG · 2-azanyl-9-[(2~{R},3~{R},4~{S})-3-oxidanyl-4-[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxy-oxolan-2-yl]-1~{H}-purin-6-one

TG, 2-azanyl-9-[(2~{R},3~{R},4~{S})-3-oxidanyl-4-[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxy-oxolan-2-yl]-1~{H}-purin-6-one (C9 H11 N5 O7 P, 332.2 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (4 PDB entries).…

Component
TG
Formula
C9 H11 N5 O7 P
Class
ligand
Structures
7
PDB entries
4

Binding sites

TG in 7 structures; the first of them:

  • 6U89 · RNA duplex, bound with TNA monomer · TG A101 · binds A7, LCC1, TLN2
  • 6U8F · RNA hairpin, bound with TNA monomer · TG A101 · binds G13, C14, A15, U22, C1
  • 7LNG · TNA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand… · TG A103 · binds C13, LCC106
  • 6MU5 · Bst DNA polymerase I TNA/DNA binary complex · TG T4 · binds TYR719, ASN782
  • 6U89 · RNA duplex, bound with tna monomer · TG A101 · binds A7, LCC1, TLN2
  • 6U8F · RNA hairpin, bound with tna monomer · TG A101 · binds G13, C14, A15, U22, C1
  • 7LNG · Tna modification at 3' end of RNA primer complex with guanosine dinucleotide ligand… · TG A103 · binds C13, LCC106

Residues it binds most

C 6, LCC 8, A 6, ASN 4, TLN 4, DC 3, DG 2, SER 3, DA 2, G 2 (residue and the binding sites it lines).

Found with

  • GP3 · Diguanosine-5'-triphosphate
  • LCG · [(1R,3R,4R,7S)-7-hydroxy-3-(guanin-9-yl)-2,5-dioxabicyclo[2.2.1]hept-1-yl]methyl dihydrogen phosphate
  • FA2 · 5-(6-amino-9H-purin-9-yl)-4-hydroxytetrahydrofuran-3-yl dihydrogen phosphate
  • TC · 4-azanyl-1-[(2~{R},3~{R},4~{S})-3-oxidanyl-4-[oxidanyl-bis(oxidanylidene)-$L^{6}-phosphanyl]oxy-oxolan-2-yl]pyrimidin-2-one
  • TFT · (L)-alpha-threofuranosyl-thymine-3'-monophosphate
  • SO4 · Sulfate ion

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