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Ligand · TDX

TDX · Thymidine-5'-diphospho-beta-D-xylose

TDX, Thymidine-5'-diphospho-beta-D-xylose (C15 H24 N2 O15 P2, 534.3 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
TDX
Formula
C15 H24 N2 O15 P2
Class
ligand
Structures
6
PDB entries
3

Binding sites

TDX in 6 structures; the first of them:

  • 1KEP · The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis… · TDX A3500 · binds SER86, ASN88, THR125, GLU127, TYR161, ASN190, LYS200, ARG225 and 2 more
  • 1NZC · The high resolution structures of RmlC from Streptococcus suis in complex with… · TDX A9002 · binds GLN61, ASN63, ARG73, HIS76, GLU78, LYS82, ASN127, TYR140 and 7 more
  • 1OC2 · The structure of NADH in the dTDP-D-glucose dehydratase (RmlB) enzyme · TDX A1349 · binds SER86, HIS87, ASN88, ASP89, THR125, ASP126, GLU127, TYR161 and 16 more
  • 1KEP · The crystal structure of dtdp-D-glucose 4,6-dehydratase (rmlb) from streptococcus suis… · TDX A3500 · binds SER86, ASN88, THR125, GLU127, TYR161, ASN190, LYS200, ARG225 and 2 more
  • 1NZC · The high resolution structures of rmlc from streptococcus suis in complex with… · TDX A9002 · binds GLN61, ASN63, ARG73, HIS76, GLU78, LYS82, ASN127, TYR140 and 7 more
  • 1OC2 · The structure of NADH in the dtdp-D-glucose dehydratase (rmlb) enzyme · TDX A1349 · binds SER86, HIS87, ASN88, ASP89, THR125, ASP126, GLU127, TYR161 and 16 more

Residues it binds most

ASN 16, ARG 16, TYR 16, GLU 16, HIS 14, LYS 16, PHE 14, ASP 10, GLN 14, SER 10 (residue and the binding sites it lines).

Found with

  • NAD · Nicotinamide-adenine-dinucleotide
  • SO4 · Sulfate ion
  • NI · Nickel (II) ion

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