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Ligand · TAP

TAP · 7-thionicotinamide-adenine-dinucleotide phosphate

TAP, 7-thionicotinamide-adenine-dinucleotide phosphate (C21 H28 N7 O16 P3 S, 759.5 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
TAP
Formula
C21 H28 N7 O16 P3 S
Class
ligand
Structures
12
PDB entries
6

Binding sites

TAP in 12 structures; the first of them:

  • 1DR2 · 2.3 ångströms crystal structure of chicken liver dihydrofolate reductase complexed with… · TAP A191 · binds VAL8, ALA9, ILE16, GLY17, LYS18, GLY20, ASN21, LEU22 and 22 more
  • 1DR3 · 2.3 ångströms crystal structure of chicken liver dihydrofolate reductase complexed with… · TAP A191 · binds VAL8, ALA9, ILE16, GLY17, LYS18, GLY20, ASN21, LEU22 and 23 more
  • 1PT9 · Crystal Structure Analysis of the DIII Component of Transhydrogenase with a… · TAP A300 · binds GLY53, TYR54, GLY55, ALA58, ALA59, VAL86, ALA87, GLY88 and 21 more
  • 4AJA · 3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II)… · TAP A501 · binds ILE37, LEU103, THR104, THR105, VAL107, ASN115, GLY321, THR338 and 12 more
  • 4AJB · 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with Isocitrate… · TAP A501 · binds ILE37, LEU103, THR104, THR105, ASN115, GLY321, THR338, HIS339 and 11 more
  • 4GO2 · Crystal structure of the c-terminal domain of 10'formyltetrahydrofolate dehydrogenase in… · TAP A3009 · binds VAL570, ILE571, PRO572, TRP573, LYS597, PRO598, ALA599, GLN600 and 20 more
  • 1DR2 · 2.3 ångströms crystal structure of chicken liver dihydrofolate reductase complexed with… · TAP A191 · binds VAL8, ALA9, ILE16, GLY17, LYS18, GLY20, ASN21, LEU22 and 22 more
  • 1DR3 · 2.3 ångströms crystal structure of chicken liver dihydrofolate reductase complexed with… · TAP A191 · binds VAL8, ALA9, ILE16, GLY17, LYS18, GLY20, ASN21, LEU22 and 23 more
  • 1PT9 · Crystal structure analysis of the diii component of transhydrogenase with a… · TAP A300 · binds GLY53, TYR54, GLY55, ALA58, ALA59, VAL86, ALA87, GLY88 and 21 more
  • 4AJA · 3D structure of E. COLI isocitrate dehydrogenase in complex with isocitrate, CALCIUM(II)… · TAP A501 · binds ILE37, LEU103, THR104, THR105, VAL107, ASN115, GLY321, THR338 and 12 more
  • 4AJB · 3D structure of E. COLI isocitrate dehydrogenase K100M mutant in complex with isocitrate… · TAP A501 · binds ILE37, LEU103, THR104, THR105, ASN115, GLY321, THR338, HIS339 and 11 more
  • 4GO2 · Crystal structure of the C-terminal domain of 10'FORMYLTETRAHYDROFOLATE dehydrogenase in… · TAP A3009 · binds VAL570, ILE571, PRO572, TRP573, LYS597, PRO598, ALA599, GLN600 and 20 more

Residues it binds most

GLY 20, ALA 20, SER 16, VAL 20, THR 20, LYS 20, LEU 18, ILE 16, PRO 16, GLU 12 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • CA · Calcium ion
  • ICT · Isocitric acid
  • GOL · Glycerol
  • HBI · 7,8-dihydrobiopterin
  • MG · Magnesium ion

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