Ligand · T5A
T5A · P1-(5'-adenosyl)p5-(5'-thymidyl)pentaphosphate
T5A, P1-(5'-adenosyl)p5-(5'-thymidyl)pentaphosphate (C20 H30 N7 O23 P5, 891.4 g/mol), in the MolNFT structures on GenesisL1: bound in 14 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…
- Component
- T5A
- Formula
- C20 H30 N7 O23 P5
- Class
- ligand
- Structures
- 14
- PDB entries
- 7
Binding sites
T5A in 14 structures; the first of them:
- 1MRN · Crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with… · T5A A301 · binds ASP9, PHE36, PRO37, TYR39, ASP46, ALA49, GLU50, LEU52 and 14 more
- 1P75 · Crystal structure of EHV4-TK complexed with TP5A · T5A A501 · binds TYR34, GLY35, ILE36, GLY37, LYS38, SER39, THR40, GLU60 and 19 more
- 1P7C · Crystal Structure of HSV1-TK complexed with TP5A · T5A A503 · binds PRO57, HIS58, GLY59, MET60, GLY61, LYS62, THR63, THR64 and 22 more
- 2WWH · Plasmodium falciparum thymidylate kinase in complex with AP5dT · T5A A211 · binds LEU16, ASP17, ARG18, SER19, GLY20, LYS21, SER22, THR23 and 23 more
- 3TMK · Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor… · T5A A217 · binds LEU13, ASP14, ARG15, THR16, GLY17, LYS18, THR19, THR20 and 24 more
- 4TMK · Complex of E. COLI thymidylate kinase with the bisubstrate inhibitor TP5A · T5A A214 · binds LEU11, GLU12, GLY13, ALA14, GLY15, LYS16, THR17, THR18 and 19 more
- 4UXH · Leishmania major Thymidine Kinase in complex with AP5dT · T5A A1180 · binds PRO12, MET13, PHE14, ALA15, GLY16, LYS17, THR18, THR19 and 23 more
- 1MRN · Crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with… · T5A A301 · binds ASP9, PHE36, PRO37, TYR39, ASP46, ALA49, GLU50, LEU52 and 14 more
- 1P75 · Crystal structure of EHV4-tk complexed with TP5A · T5A A501 · binds TYR34, GLY35, ILE36, GLY37, LYS38, SER39, THR40, GLU60 and 19 more
- 1P7C · Crystal structure of HSV1-tk complexed with TP5A · T5A A503 · binds PRO57, HIS58, GLY59, MET60, GLY61, LYS62, THR63, THR64 and 22 more
- 2WWH · Plasmodium falciparum thymidylate kinase in complex with AP5DT · T5A A211 · binds LEU16, ASP17, ARG18, SER19, GLY20, LYS21, SER22, THR23 and 23 more
- 3TMK · Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor… · T5A A217 · binds LEU13, ASP14, ARG15, THR16, GLY17, LYS18, THR19, THR20 and 24 more
- 4TMK · Complex of E. COLI thymidylate kinase with the bisubstrate inhibitor TP5A · T5A A214 · binds LEU11, GLU12, GLY13, ALA14, GLY15, LYS16, THR17, THR18 and 19 more
- 4UXH · Leishmania major thymidine kinase in complex with AP5DT · T5A A1180 · binds PRO12, MET13, PHE14, ALA15, GLY16, LYS17, THR18, THR19 and 23 more
Residues it binds most
ARG 40, TYR 40, GLY 38, LYS 38, THR 38, GLU 40, PHE 38, ASP 34, LEU 36, SER 36 (residue and the binding sites it lines).
Found with
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