SUI · (3-amino-2,5-dioxo-1-pyrrolidinyl)acetic acid

Binding sites

SUI in 17 structures; the first of them:

• 1GKT · Neutron laue diffraction structure of endothiapepsin complexed with transition state… · SUI A54 · binds GLU52, VAL53, GLN56, THR57, THR117, SER120
• 1GVT · Endothiapepsin complex with cp-80,794 · SUI A54 · binds GLU52, VAL53, GLN56, THR57, THR117, SER120
• 1GVU · Endothiapepsin complex with H189 · SUI A54 · binds GLU52, VAL53, GLN56, THR57, THR117, SER120
• 1GVV · Five atomic resolution structures of endothiapepsin inhibitor complexes; implications for… · SUI A54 · binds GLU52, VAL53, GLN56, THR57, THR117, SER120
• 1GVW · Endothiapepsin complex with pd-130,328 · SUI A54 · binds GLU52, VAL53, GLN56, THR57, THR117, SER120
• 1GVX · Endothiapepsin complexed with H256 · SUI A54 · binds GLU52, VAL53, GLN56, THR57, THR117, SER120
• 1OEW · Atomic resolution structure of native endothiapepsin · SUI A54 · binds GLU52, VAL53, GLN55, THR56, THR116, SER119
• 1OEX · Atomic resolution structure of endothiapepsin in complex with a hydroxyethylene… · SUI A54 · binds GLU52, VAL53, GLN55, THR56, THR116, SER119
• 2JJI · Endothiapepsin in complex with a gem-diol inhibitor. · SUI A54 · binds GLU52, VAL53, GLN56, THR57, THR117, SER120
• 2JJJ · Endothiapepsin in complex with a gem-diol inhibitor. · SUI A54 · binds GLU52, VAL53, GLN56, THR57, THR117, SER120
• 2OWC · Structure of a covalent intermediate in thermus thermophilus amylomaltase · SUI A370 · binds PHE368, ASP369, MET372, GLU373, ASN374, LEU377, PHE413
• 2OWW · Covalent intermediate in amylomaltase in complex with the acceptor analog 4-deoxyglucose · SUI A370 · binds PHE368, ASP369, MET372, GLU373, ASN374, LEU377, PHE413
• 2OWX · Thermus thermophilus amylomaltase at pH 5.6 · SUI A370 · binds PHE368, ASP369, MET372, GLU373, ASN374, LEU377, PHE413
• 2VS2 · Neutron diffraction structure of endothiapepsin in complex with a gem- diol inhibitor. · SUI A54 · binds GLU52, VAL53, GLN56, THR57, THR117, SER120
• 3URI · Endothiapepsin-DB5 complex. · SUI A54 · binds GLU52, VAL53, GLN55, THR56, THR116, SER119
• 3URJ · Type IV native endothiapepsin · SUI A54 · binds GLU52, VAL53, GLN55, THR56, THR116, SER119
• 3URL · Endothiapepsin-DB6 complex. · SUI A54 · binds GLU52, VAL53, GLN55, THR56, THR116, SER119

Residues it binds most

THR 14, GLU 17, GLN 14, SER 14, VAL 14, PHE 3, ASN 3, ASP 3, LEU 3, MET 3 (residue and the binding sites it lines).

Found with

• SO4 · Sulfate ion
• GOL · Glycerol
• 0QS · N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide
• MLI · Malonate ion
• AC1 · 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose
• BOC · Tert-butyl hydrogen carbonate
• PUK · N-[(2S)-2-amino-3-phenylpropyl]-L-phenylalanine
• GLC · alpha-D-glucopyranose
• 0EM · N-(tert-butoxycarbonyl)-L-phenylalanyl-N-{(1S)-1-[(R)-hydroxy(2-{[(2S)-2-methylbutyl]amino}-2-oxoethyl)phosphoryl]-3-methylbutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide
• 0GM · N-[(5S,9S,10S,13S)-9-hydroxy-5,10-bis(2-methylpropyl)-4,7,12,16-tetraoxo-3,6,11,17-tetraazabicyclo[17.3.1]tricosa-1(23),19,21-trien-13-yl]-3-(naphthalen-1-yl)-2-(naphthalen-1-ylmethyl)propanamide
• 13E · N-[(2S)-2-amino-3-phenylpropyl]-L-methionine
• 2ZS · N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R,2S)-1-(cyclohexylmethyl)-2-hydroxy-3-(1-methylethoxy)-3-oxopropyl]-S-methyl-L-cysteinamide