Ligand · SK8
SK8 · 6-(4-fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole
SK8, 6-(4-fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole (C16 H12 F N3 S, 297.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å…
- Component
- SK8
- Formula
- C16 H12 F N3 S
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
SK8 in 4 structures; the first of them:
- 4LL5 · Crystal Structure of Pim-1 in complex with the fluorescent compound SKF86002 · SK8 A401 · binds LEU44, GLY45, PHE49, VAL52, ALA65, LYS67, GLU89, LEU120 and 7 more
- 4LUD · Crystal Structure of HCK in complex with the fluorescent compound SKF86002 · SK8 A603 · binds LEU273, VAL281, ALA293, VAL294, LYS295, ILE336, THR338, GLU339 and 7 more
- 4LL5 · Crystal structure of pim-1 in complex with the fluorescent compound SKF86002 · SK8 A401 · binds LEU44, GLY45, PHE49, VAL52, ALA65, LYS67, GLU89, LEU120 and 7 more
- 4LUD · Crystal structure of hck in complex with the fluorescent compound SKF86002 · SK8 A603 · binds LEU273, VAL281, ALA293, VAL294, LYS295, ILE336, THR338, GLU339 and 7 more
Residues it binds most
LEU 6, VAL 6, ALA 6, ASP 6, GLU 6, ILE 6, LYS 6, PHE 6, GLY 4, MET 4 (residue and the binding sites it lines).
Found with
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