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Ligand · SHR

SHR · N-(5-amino-5-carboxypentyl)glutamic acid

SHR, N-(5-amino-5-carboxypentyl)glutamic acid (C11 H20 N2 O6, 276.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
SHR
Formula
C11 H20 N2 O6
Class
ligand
Structures
4
PDB entries
2

Binding sites

SHR in 4 structures; the first of them:

  • 1E5Q · Ternary complex of saccharopine reductase from Magnaporthe grisea, NADPH and saccharopine · SHR A501 · binds TYR78, THR98, SER99, TYR100, ASP126, PRO127, CYS155, GLY156 and 9 more
  • 3UH1 · Crystal Structure of Saccharopine Dehydrogenase from Saccharomyces cerevisiae with bound… · SHR A375 · binds ARG18, LYS77, PHE94, HIS96, LYS99, GLN101, GLU122, ARG131 and 10 more
  • 1E5Q · Ternary complex of saccharopine reductase from magnaporthe grisea, NADPH and saccharopine · SHR A501 · binds TYR78, THR98, SER99, TYR100, ASP126, PRO127, CYS155, GLY156 and 9 more
  • 3UH1 · Crystal structure of saccharopine dehydrogenase from saccharomyces cerevisiae with bound… · SHR A375 · binds ARG18, LYS77, PHE94, HIS96, LYS99, GLN101, GLU122, ARG131 and 10 more

Residues it binds most

GLY 18, ARG 18, THR 16, TYR 16, ALA 18, ASP 18, PRO 18, SER 18, ASN 16, CYS 16 (residue and the binding sites it lines).

Found with

  • NAI · 1,4-dihydronicotinamide adenine dinucleotide
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
  • GOL · Glycerol

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