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Ligand · SGH

SGH · 1-[4-methyl-3-(trifluoromethyl)phenyl]-2-phenyl-imidazole

SGH, 1-[4-methyl-3-(trifluoromethyl)phenyl]-2-phenyl-imidazole (C17 H13 F3 N2, 302.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
SGH
Formula
C17 H13 F3 N2
Class
ligand
Structures
2
PDB entries
1

Binding sites

SGH in 2 structures; the first of them:

  • 7AZ1 · 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1013 · SGH A301 · binds CSO38, ASN42, SER45, GLU115, PHE119, LYS122, PRO167, ILE168 and 4 more
  • 7AZ1 · 14-3-3 sigma with PIN1 binding site PS72 and covalently bound LVD1013 · SGH A301 · binds CSO38, ASN42, SER45, PHE119, LYS122, PRO167, ILE168, GLY171 and 2 more

Residues it binds most

ILE 2, ASN 2, CSO 2, GLY 2, LYS 2, PHE 2, PRO 2, SER 2, TRP 2, ASP 1 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • CL · Chloride ion

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