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Ligand · S4N

S4N · (R)-N2-(4-(cyclopropylmethoxy)-3,5-difluorophenyl)-5-(3-methylpiperazin-1-yl)-N4-(tetrahydro-2H-pyran-4-yl)pyrimidine-2,4-diamine

S4N, (R)-N2-(4-(cyclopropylmethoxy)-3,5-difluorophenyl)-5-(3-methylpiperazin-1-yl)-N4-(tetrahydro-2H-pyran-4-yl)pyrimidine-2,4-diamine (C24 H32 F2 N6 O2, 474.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry).…

Component
S4N
Formula
C24 H32 F2 N6 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

S4N in 1 structure; the first of them:

  • 7AVZ · Mertk kinase domain in complex with a bisaminopyrimidine inhibitor · S4N A901 · binds LEU593, VAL601, ALA617, ILE650, LEU671, PRO672, PHE673, MET674 and 8 more

Residues it binds most

ALA 1, ASP 1, LEU 1, MET 1, ARG 1, ASN 1, GLY 1, ILE 1, LYS 1, PHE 1 (residue and the binding sites it lines).

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