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Ligand · S1Z

S1Z · (2~{R})-2-[[3-(2~{H}-indazol-5-yl)imidazo[1,2-b]pyridazin-6-yl]amino]butan-1-ol

S1Z, (2~{R})-2-[[3-(2~{H}-indazol-5-yl)imidazo[1,2-b]pyridazin-6-yl]amino]butan-1-ol (C17 H18 N6 O, 322.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
S1Z
Formula
C17 H18 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

S1Z in 2 structures; the first of them:

  • 7AVQ · Crystal structure of haspin in complex with disubstituted imidazo[1,2- b]pyridazine… · S1Z A801 · binds ILE490, GLY491, GLU492, PHE495, VAL498, ALA509, LYS511, ILE557 and 9 more
  • 7AVQ · Crystal structure of haspin in complex with disubstituted IMIDAZO[1,2- B]PYRIDAZINE… · S1Z A801 · binds ILE490, GLY491, GLU492, PHE495, VAL498, ALA509, LYS511, ILE557 and 9 more

Residues it binds most

GLY 2, ILE 2, PHE 2, ASP 2, GLU 2, ALA 2, LEU 2, LYS 2, VAL 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • GOL · Glycerol
  • MPD · (4S)-2-methyl-2,4-pentanediol

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