GL1X · GenesisL1 explorer

Ligand · RTT

RTT · (2'R,5'S,12'R)-12'-cyclohexyl-2'-[2-(3,4-dimethoxyphenyl)ethyl]-3',19'-dioxa-10',13',16'-triazaspiro[cyclopropane-1,15'- tricyclo[18.3.1.0-5,10]tetracosane]-1'(24'),20',22'-triene-4',11',14',17'-tetrone

RTT, (2'R,5'S,12'R)-12'-cyclohexyl-2'-[2-(3,4-dimethoxyphenyl)ethyl]-3',19'-dioxa-10',13',16'-triazaspiro[cyclopropane-1,15'- tricyclo[18.3.1.0-5,10]tetracosane]-1'(24'),20',22'-triene-4',11',14',17'-tetrone (C37 H47 N3 O8, 661.8 g/mol)…

Component
RTT
Formula
C37 H47 N3 O8
Class
ligand
Structures
2
PDB entries
1

Binding sites

RTT in 2 structures; the first of them:

  • 7AOU · The Fk1 domain of FKBP51 in complex with (2'R,5'S,12'R)-12'-cyclohexyl-2'-[2-(3,4-dimethox… · RTT A301 · binds TYR57, GLY59, LYS60, LEU61, ASP68, SER70, HIS71, PHE77 and 11 more
  • 7AOU · The FK1 domain of FKBP51 in complex with (2'R,5'S,12'R)-12'… · RTT A301 · binds TYR57, GLY59, LYS60, LEU61, ASP68, SER70, HIS71, PHE77 and 11 more

Residues it binds most

GLY 2, ILE 2, LEU 2, LYS 2, PHE 2, TYR 2, ALA 2, ASP 2, GLN 2, HIS 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.