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Ligand · RTH

RTH · 6-[2-(3,3-dimethylbut-1-yn-1-yl)phenyl]quinolin-2-amine

RTH, 6-[2-(3,3-dimethylbut-1-yn-1-yl)phenyl]quinolin-2-amine (C21 H20 N2, 300.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
RTH
Formula
C21 H20 N2
Class
ligand
Structures
2
PDB entries
1

Binding sites

RTH in 2 structures; the first of them:

  • 3RTH · Structure of Bace-1 (Beta-Secretase) in Complex with… · RTH A397 · binds LEU30, ASP32, GLY34, SER35, VAL69, TYR71, GLY74, LYS75 and 9 more
  • 3RTH · Structure of bace-1 (beta-secretase) in complex with 6-(2-(3,3… · RTH A397 · binds LEU30, ASP32, GLY34, SER35, VAL69, TYR71, GLY74, LYS75 and 9 more

Residues it binds most

ASP 2, GLY 2, ILE 2, LYS 2, LEU 2, PHE 2, SER 2, THR 2, TRP 2, TYR 2 (residue and the binding sites it lines).

Found with

  • IOD · Iodide ion

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