GL1X · GenesisL1 explorer

Ligand · RMQ

RMQ · (3~{R})-4-[4-[[(2~{S})-2-[[2,2-bis(fluoranyl)-2-phenyl-ethanoyl]amino]-3-(2-chlorophenyl) propanoyl]amino]phenyl]-3-[[(2~{S})-3-methyl-2-[2-[2-[(2-methylpropan-2-yl) oxycarbonylamino]ethoxy]ethanoylamino]butanoyl]amino]b utanoic acid

RMQ, (3~{R})-4-[4-[[(2~{S})-2-[[2,2-bis(fluoranyl)-2-phenyl-ethanoyl]amino]-3-(2-chlorophenyl) propanoyl]amino]phenyl]-3-[[(2~{S})-3-methyl-2-[2-[2-[(2-methylpropan-2-yl) oxycarbonylamino]ethoxy]ethanoylamino]butanoyl]amino]b utanoic acid…

Component
RMQ
Formula
C41 H50 Cl F2 N5 O9
Class
ligand
Structures
2
PDB entries
1

Binding sites

RMQ in 2 structures; the first of them:

  • 7AMG · IL-17A in complex with small molecule modulators · RMQ A500 · binds TYR62, PRO63, VAL65, ILE66, TRP67, GLN94, GLU95, ILE96 and 13 more
  • 7AMG · Il-17A in complex with small molecule modulators · RMQ A500 · binds TYR62, PRO63, VAL65, ILE66, TRP67, GLN94, GLU95, ILE96 and 10 more

Residues it binds most

LEU 4, ILE 4, VAL 4, PRO 4, GLU 4, GLN 4, TYR 4, LYS 4, TRP 4 (residue and the binding sites it lines).

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