Ligand · RMF
RMF · ~{N}-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine
RMF, ~{N}-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine (C21 H20 Cl2 N10 O, 499.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every…
- Component
- RMF
- Formula
- C21 H20 Cl2 N10 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 2
Binding sites
RMF in 2 structures; the first of them:
- 8BU5 · Structure of DDB1 bound to SR-4835-engaged CDK12-cyclin K · RMF B1101 · binds ASN907, ARG928, ARG947, ILE733, GLY734, GLU735, VAL741, ALA754 and 13 more
- 9FMR · Structure of DDB1/Cdk12/Cyclin K with molecular glue SR-4835 · RMF B1101 · binds ASN907, ARG928, ARG947, ILE732, ILE733, GLY734, GLU735, GLY736 and 15 more
Residues it binds most
ASP 6, GLU 6, ALA 6, ARG 6, VAL 6, ILE 6, MET 6, PHE 6, GLY 6, ASN 6 (residue and the binding sites it lines).
Found with
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