RLZ · ~{N}-[4-[(4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15, 19-tetramethyl-2,6,9,12-tetrakis(oxidanylidene)-1-oxa-5,8,11-triazacyclononadec-15-en-10-yl]butyl]-~{N}'-[5-methoxy-2-[(~{Z})-(3,4,5-trimethoxyphenyl) diazenyl]phenyl]butanediamide

Binding sites

RLZ in 4 structures; the first of them:

• 7AHN · Cryo-EM structure of F-actin stabilized by cis-optoJASP-8 · RLZ C404 · binds THR194, ARG196, GLY197, TYR198, SER199, PHE200, GLU205, LEU242 and 17 more
• 7AHQ · Cryo-EM structure of F-actin stabilized by trans-optoJASP-8 · RLZ A404 · binds GLU72, HIC73, ILE75, THR77, LEU110, PRO112, ALA114, ASN115 and 6 more
• 7AHN · Cryo-EM structure of F-actin stabilized by cis-optojasp-8 · RLZ C404 · binds THR194, ARG196, GLY197, TYR198, SER199, PHE200, GLU205, LEU242 and 13 more
• 7AHQ · Cryo-EM structure of F-actin stabilized by trans-optojasp-8 · RLZ A404 · binds GLU72, HIC73, ILE75, THR77, LEU110, PRO112, ALA114, ARG177 and 5 more

Residues it binds most

ARG 20, LEU 20, GLU 20, ILE 20, MET 17, THR 19, ALA 20, ASP 20, HIC 20, PRO 20 (residue and the binding sites it lines).

Found with

• ADP · Adenosine-5'-diphosphate
• MG · Magnesium ion
• PO4 · Phosphate ion