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Ligand · RGZ

RGZ · (R)-rosiglitazone

RGZ, (R)-rosiglitazone (C18 H19 N3 O3 S, 357.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
RGZ
Formula
C18 H19 N3 O3 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

RGZ in 4 structures; the first of them:

  • 4A7A · Crystal structure of human monoamine oxidase B (MAO B) in complex with rosiglitazone · RGZ A601 · binds TYR60, PRO102, PRO104, TRP119, LEU164, LEU167, PHE168, LEU171 and 9 more
  • 7M24 · Human carbonic anhydrase II in complex with (R)-rosiglitazone · RGZ A302 · binds GLN92, HIS94, HIS96, GLU106, HIS119, PHE131, GLY132, VAL135 and 8 more
  • 4A7A · Crystal structure of human monoamine oxidase B (mao B) in complex with rosiglitazone · RGZ A601 · binds TYR60, PRO102, PRO104, TRP119, LEU164, LEU167, PHE168, LEU171 and 9 more
  • 7M24 · Human carbonic anhydrase II in complex with (R)-rosiglitazone · RGZ A302 · binds GLN92, HIS94, HIS96, GLU106, HIS119, PHE131, GLY132, VAL135 and 8 more

Residues it binds most

LEU 6, TYR 4, ILE 4, PRO 6, PHE 6, GLN 6, HIS 2, TRP 6, CYS 4, THR 2 (residue and the binding sites it lines).

Found with

  • FAD · Flavin-adenine dinucleotide
  • ZN · Zinc ion

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