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Ligand · RGT

RGT · 2-amino-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-ribofuranosyl}-9H-purin-6-yl 5-O-phosphono-beta-D-ribofuranoside

RGT, 2-amino-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-ribofuranosyl}-9H-purin-6-yl 5-O-phosphono-beta-D-ribofuranoside (C15 H25 N5 O21 P4, 735.3 g/mol), in the MolNFT structures on GenesisL1: bound in…

Component
RGT
Formula
C15 H25 N5 O21 P4
Class
ligand
Structures
2
PDB entries
1

Binding sites

RGT in 2 structures; the first of them:

  • 3DZI · Crystal structure of human CD38 extracellular domain, ribose-5'-phosphate… · RGT A301 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP155 and 11 more
  • 3DZI · Crystal structure of human CD38 extracellular domain, ribose-5'- phosphate… · RGT A301 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP155 and 11 more

Residues it binds most

SER 2, TRP 2, ARG 2, ASP 2, GLU 2, LEU 2, PHE 2, LYS 2, THR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • GTP · Guanosine-5'-triphosphate
  • N · Any 5'-monophosphate nucleotide

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