QNG · N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2, 2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bs,4ar)-5,5-difluoro-3-(trifluoromethyl)-3B,4,4A,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide

Binding sites

QNG in 7 structures; the first of them:

• 6V2F · Crystal structure of the HIV capsid hexamer bound to the small molecule long-acting… · QNG A300 · binds GLN50, ASN53, THR54, LEU56, ASN57, GLN63, MET66, GLN67 and 7 more
• 9DWD · Gag CA-SP1 immature lattice bound with Lenacapavir from enveloped virus like particles… · QNG A301 · binds GLN50, ASN53, THR54, LEU56, ASN57, VAL59, GLN63, MET66 and 16 more
• 6V2F · Crystal structure of the HIV capsid hexamer bound to the small molecule long-acting… · QNG A300 · binds GLN50, ASN53, THR54, LEU56, ASN57, GLN63, MET66, GLN67 and 7 more
• 6VKV · Co-crystal structure of gs-6207 bound to HIV-1 capsid hexamer · QNG A301 · binds GLN50, ASN53, THR54, LEU56, ASN57, GLN63, MET66, GLN67 and 7 more
• 7RHN · Co-crystal structure of Q67H mutant of disulfide stabilized HIV-1 ca hexamer and… · QNG C301 · binds ASN53, LEU56, ASN57, GLN63, MET66, LEU69, LYS70, ILE73 and 5 more
• 7RJ2 · Co-crystal structure of lenacapavir bound to Q67H/N74D mutant of disulfide stabilized… · QNG C301 · binds GLN50, ASN53, THR54, LEU56, ASN57, GLN63, MET66, HIS67 and 7 more
• 7RJ4 · Co-crystal structure of lenacapavir bound to N74D mutant of disulfide stabilized HIV-1 ca… · QNG A301 · binds GLN50, ASN53, THR54, LEU56, ASN57, GLN63, MET66, GLN67 and 7 more

Residues it binds most

ASN 38, GLN 38, LEU 38, THR 38, ILE 38, LYS 38, TYR 38, MET 38, ALA 37, ARG 14 (residue and the binding sites it lines).

Found with

• CL · Chloride ion
• IOD · Iodide ion
• IHP · Inositol hexakisphosphate