GL1X · GenesisL1 explorer

Ligand · QHF

QHF · N-[(2S,4S)-1-({4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]piperidin-1-yl}sulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide

QHF, N-[(2S,4S)-1-({4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]piperidin-1-yl}sulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide (C23 H34 F N5 O5 S, 511.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
QHF
Formula
C23 H34 F N5 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

QHF in 2 structures; the first of them:

  • 3Q2H · Adamts1 in complex with N-hydroxyformamide inhibitors of ADAM-TS4 · QHF A1 · binds ASP116, THR117, LEU118, GLY119, MET120, ALA121, VAL123, GLN142 and 12 more
  • 3Q2H · ADAMTS1 in complex with N-hydroxyformamide inhibitors of adam-TS4 · QHF A1 · binds ASP116, THR117, LEU118, GLY119, MET120, ALA121, VAL123, GLN142 and 12 more

Residues it binds most

HIS 4, MET 4, ALA 4, LEU 4, PHE 4, THR 4, ASP 4, GLN 4, GLU 4, GLY 4 (residue and the binding sites it lines).

Found with

  • CD · Cadmium ion
  • MG · Magnesium ion
  • NA · Sodium ion
  • NI · Nickel (II) ion
  • ZN · Zinc ion

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