GL1X · GenesisL1 explorer

Ligand · Q74

Q74 · 2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid

Q74, 2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid (C17 H10 F3 N3 O2 S, 377.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
Q74
Formula
C17 H10 F3 N3 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

Q74 in 2 structures; the first of them:

  • 3G5E · Human aldose reductase complexed with IDD 740 inhibitor · Q74 A320 · binds TRP20, TYR48, TRP79, CYS80, HIS110, TRP111, THR113, PHE115 and 9 more
  • 3G5E · Human aldose reductase complexed with idd 740 inhibitor · Q74 A320 · binds TRP20, TYR48, TRP79, CYS80, HIS110, TRP111, THR113, PHE115 and 9 more

Residues it binds most

TRP 2, CYS 2, PHE 2, TYR 2, ALA 2, HIS 2, LEU 2, PRO 2, THR 2 (residue and the binding sites it lines).

Found with

  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate

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