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Ligand · PNP

PNP · Methyl-phosphonic acid mono-(4-nitro-phenyl) ester

PNP, Methyl-phosphonic acid mono-(4-nitro-phenyl) ester (C7 H8 N O5 P, 217.1 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
PNP
Formula
C7 H8 N O5 P
Class
ligand
Structures
4
PDB entries
2

Binding sites

PNP in 4 structures; the first of them:

  • 1KNO · Crystal structure of the complex of a catalytic antibody Fab with a transition state… · PNP B551 · binds LEU89, TYR91, TYR96, PHE98, HIS35, VAL37, TRP47, TYR50 and 5 more
  • 1ZED · Alkaline phosphatase from human placenta in complex with p-nitrophenyl-phosphonate · PNP A901 · binds ASP91, PHE107, GLN108, ARG166, HIS432
  • 1KNO · Crystal structure of the complex of a catalytic antibody Fab with a transition state… · PNP B551 · binds LEU89, TYR91, TYR96, PHE98, HIS35, VAL37, TRP47, TYR50 and 5 more
  • 1ZED · Alkaline phosphatase from human placenta in complex with P- nitrophenyl-phosphonate · PNP A901 · binds ASP91, PHE107, GLN108, ARG166, HIS432

Residues it binds most

TYR 6, TRP 6, ASP 8, HIS 8, LEU 8, PHE 8, ARG 4, GLY 6, VAL 6, ALA 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • CA · Calcium ion
  • MG · Magnesium ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • PO3 · Phosphite ion

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