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Ligand · PFD

PFD · 5-(2-ethoxyethyl)-5-[4-(4-fluorophenoxy)phenoxy]pyrimidine-2,4,6(1H,3H,5H)-trione

PFD, 5-(2-ethoxyethyl)-5-[4-(4-fluorophenoxy)phenoxy]pyrimidine-2,4,6(1H,3H,5H)-trione (C20 H19 F N2 O6, 402.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
PFD
Formula
C20 H19 F N2 O6
Class
ligand
Structures
2
PDB entries
1

Binding sites

PFD in 2 structures; the first of them:

  • 1YOU · Crystal structure of the catalytic domain of MMP-13 complexed with a potent… · PFD A998 · binds LEU184, LEU185, ALA186, HIS187, LEU218, VAL219, HIS222, GLU223 and 9 more
  • 1YOU · Crystal structure of the catalytic domain of mmp-13 complexed with a potent… · PFD A998 · binds LEU184, LEU185, ALA186, HIS187, LEU218, VAL219, HIS222, GLU223 and 9 more

Residues it binds most

HIS 4, LEU 4, ALA 4, GLU 4, ILE 4, PHE 4, PRO 4, THR 4, TYR 4, VAL 4 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion

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