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Ligand · PAL

PAL · N-(phosphonacetyl)-L-aspartic acid

PAL, N-(phosphonacetyl)-L-aspartic acid (C6 H10 N O8 P, 255.1 g/mol), in the MolNFT structures on GenesisL1: bound in 10 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
PAL
Formula
C6 H10 N O8 P
Class
ligand
Structures
10
PDB entries
7

Binding sites

PAL in 10 structures; the first of them:

  • 5G1N · Aspartate transcarbamoylase domain of human CAD bound to PALA · PAL A3226 · binds SER1973, THR1974, ARG1975, THR1976, ARG2024, HIS2052, GLN2055, ARG2085 and 6 more
  • 6JKT · Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with… · PAL A401 · binds ASP61, SER62, SER63, ARG64, THR65, ARG113, HIS141, GLN144 and 9 more
  • 6PNZ · The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus… · PAL A301 · binds ASN47, SER48, THR49, ARG50, THR51, ARG100, HIS127, GLN130 and 8 more
  • 6YSP · Arabidopsis aspartate transcarbamoylase complex with PALA and carbamoyl phosphate · PAL C401 · binds SER163, LYS166, PRO133, SER134, THR135, ARG136, THR137, ARG138 and 10 more
  • 6JKT · Crystal structure of aspartate transcarbamoylase from trypanosoma cruzi in complex with… · PAL A401 · binds SER62, SER63, ARG64, THR65, ARG113, HIS141, ARG174, THR175 and 6 more
  • 6PNZ · The structure of the aspartate transcarbamoylase trimer from staphylococcus aureus… · PAL A301 · binds ASN47, SER48, THR49, ARG50, THR51, ARG100, HIS127, GLN130 and 8 more
  • 6YS6 · Arabidopsis aspartate transcarbamoylase complex with pala · PAL C401 · binds SER163, LYS166, SER134, THR135, ARG136, THR137, ARG187, HIS215 and 8 more
  • 6YSP · Arabidopsis aspartate transcarbamoylase complex with pala and carbamoyl phosphate · PAL C401 · binds SER163, LYS166, SER134, THR135, ARG136, THR137, ARG187, HIS215 and 8 more
  • 6YW9 · Arabidopsis aspartate transcarbamoylase mutant F161A complex with pala · PAL A401 · binds PRO133, SER134, THR135, ARG136, THR137, ARG187, HIS215, GLN218 and 8 more
  • 8ATC · Complex of N-phosphonacetyl-L-aspartate with aspartate carbamoyltransferase. X-ray… · PAL A311 · binds SER52, THR53, ARG54, THR55, ARG105, HIS134, GLN137, ARG167 and 5 more

Residues it binds most

ARG 32, THR 32, SER 32, GLN 32, PRO 28, HIS 32, LYS 28, LEU 20, ALA 7, ASP 7 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol
  • SO4 · Sulfate ion
  • CP · Phosphoric acid mono(formamide)ester
  • ZN · Zinc ion
  • EDO · 1,2-ethanediol

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