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Ligand · P6C

P6C · 2-amino-4-isopropyl-pteridine-6-carboxylic acid

P6C, 2-amino-4-isopropyl-pteridine-6-carboxylic acid (C10 H11 N5 O2, 233.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
P6C
Formula
C10 H11 N5 O2
Class
ligand
Structures
4
PDB entries
2

Binding sites

P6C in 4 structures; the first of them:

  • 1TFM · Crystal structure of a ribosome inactivating protein in its naturally inhibited form · P6C A242 · binds TYR75, GLY108, SER109, TYR110, PRO111, ARG162, TRP193, GLY194
  • 1YF8 · Crystal structure of Himalayan mistletoe RIP reveals the presence of a natural inhibitor… · P6C A1001 · binds TYR75, GLY108, SER109, TYR110, ARG162, TRP193, GLY194, GLN195 and 1 more
  • 1TFM · Crystal structure of a ribosome inactivating protein in its naturally inhibited form · P6C A242 · binds TYR75, GLY108, SER109, TYR110, PRO111, ARG162, TRP193, GLY194
  • 1YF8 · Crystal structure of himalayan mistletoe rip reveals the presence of a natural inhibitor… · P6C A1001 · binds TYR75, GLY108, SER109, TYR110, ARG162, TRP193, GLY194, GLN195 and 1 more

Residues it binds most

GLY 4, TYR 4, ARG 4, SER 4, TRP 4, GLN 2, LEU 2, PRO 2 (residue and the binding sites it lines).

Found with

  • BGC · beta-D-glucopyranose
  • BMA · beta-D-mannopyranose
  • GAL · beta-D-galactopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • MAN · alpha-D-mannopyranose

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