P0G · 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl) ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one

Binding sites

P0G in 6 structures; the first of them:

• 6N48 · Structure of beta2 adrenergic receptor bound to BI167107, Nanobody 6B9, and a positive… · P0G A1401 · binds TRP1109, THR1110, ASP1113, VAL1114, VAL1117, CYS1191, PHE1193, ALA1200 and 9 more
• 6NI3 · B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex · P0G R1601 · binds HIS93, TRP109, THR110, ASP113, VAL114, VAL117, CYS191, PHE193 and 8 more
• 6E67 · Structure of BETA2 adrenergic receptor fused to a gs peptide · P0G A3101 · binds TRP109, THR110, ASP113, VAL114, VAL117, PHE193, ALA200, SER203 and 8 more
• 6N48 · Structure of BETA2 adrenergic receptor bound to BI167107, nanobody 6B9, and a positive… · P0G A1401 · binds TRP1109, THR1110, ASP1113, VAL1114, VAL1117, CYS1191, PHE1193, ALA1200 and 9 more
• 6NI3 · B2V2R-gs protein subcomplex of a GPCR-G protein-beta-arrestin mega- complex · P0G R1601 · binds HIS93, TRP109, THR110, ASP113, VAL114, VAL117, CYS191, PHE193 and 8 more
• 7BU7 · Structure of human BETA1 adrenergic receptor bound to bi-167107 and nanobody 6B9 · P0G A1413 · binds TRP1134, ASP1138, VAL1139, CYS1216, ASP1217, PHE1218, ALA1225, SER1228 and 7 more

Residues it binds most

PHE 7, SER 7, ASN 7, VAL 7, TYR 7, ASP 7, TRP 7, CYS 6, THR 6, ALA 5 (residue and the binding sites it lines).

Found with

• 1WV · (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate
• KBY · N-[(3R)-4-(4-tert-butylphenyl)-3-({2-[(4-methoxyphenyl)sulfanyl]-5-[methyl(propan-2-yl) sulfamoyl]benzene-1-carbonyl}amino)butanoyl]glycine
• CLR · Cholesterol
• NA · Sodium ion
• GLC · alpha-D-glucopyranose
• SO4 · Sulfate ion
• EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
• P6G · Hexaethylene glycol