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Ligand · OT7

OT7 · 5-[3-chloranyl-2-fluoranyl-6-(1,2,3,4-tetrazol-1-yl) phenyl]-2-[(1~{R})-2-cyclopropyl-1-[4-(2-methylpyrazol-3-yl)pyrazol-1-yl]ethyl]-1-oxidanyl-pyridine

OT7, 5-[3-chloranyl-2-fluoranyl-6-(1,2,3,4-tetrazol-1-yl) phenyl]-2-[(1~{R})-2-cyclopropyl-1-[4-(2-methylpyrazol-3-yl)pyrazol-1-yl]ethyl]-1-oxidanyl-pyridine (C24 H21 Cl F N9 O, 505.9 g/mol), in the MolNFT structures on GenesisL1: bound in…

Component
OT7
Formula
C24 H21 Cl F N9 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

OT7 in 2 structures; the first of them:

  • 7V16 · Factor XIa in Complex with Compound 2j · OT7 A702 · binds ARG413, HIS414, LEU415, CYS416, HIS431, CYS432, TYR521, LEU524 and 17 more
  • 7V16 · Factor xia in complex with compound 2J · OT7 A702 · binds ARG413, HIS414, LEU415, CYS416, HIS431, TYR521, LEU524, ILE528 and 16 more

Residues it binds most

GLY 2, CYS 2, ASP 2, HIS 2, LEU 2, SER 2, TYR 2, ALA 2, ARG 2, ILE 2 (residue and the binding sites it lines).

Found with

  • CIT · Citric acid

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