GL1X · GenesisL1 explorer

Ligand · OSX

OSX · 5-[1-[(1~{R})-1-[5-[3-chloranyl-2-fluoranyl-6-(1,2,3,4-tetrazol-1-yl)phenyl]-1-oxidanyl-pyridin-2-yl]-2-cyclopropyl-ethyl]pyrazol-4-yl]-4-methyl-1,3-thiazole

OSX, 5-[1-[(1~{R})-1-[5-[3-chloranyl-2-fluoranyl-6-(1,2,3,4-tetrazol-1-yl)phenyl]-1-oxidanyl-pyridin-2-yl]-2-cyclopropyl-ethyl]pyrazol-4-yl]-4-methyl-1,3-thiazole (C24 H20 Cl F N8 O S, 523.0 g/mol), in the MolNFT structures on GenesisL1…

Component
OSX
Formula
C24 H20 Cl F N8 O S
Class
ligand
Structures
2
PDB entries
1

Binding sites

OSX in 2 structures; the first of them:

  • 7V15 · Factor XIa in Complex with Compound 2i · OSX A702 · binds ARG413, HIS414, LEU415, CYS416, HIS431, CYS432, TYR521, LEU524 and 17 more
  • 7V15 · Factor xia in complex with compound 2I · OSX A702 · binds ARG413, HIS414, LEU415, CYS416, HIS431, TYR521, LEU524, ILE528 and 16 more

Residues it binds most

GLY 2, CYS 2, ASP 2, HIS 2, LEU 2, SER 2, TYR 2, ALA 2, ARG 2, ILE 2 (residue and the binding sites it lines).

Found with

  • CIT · Citric acid

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.