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Ligand · OHZ

OHZ · 1-(3-Chloro-5-trifluoromethoxy-phenyl)-3-[2-(2-hydroxy-ethyl)-phenyl]-urea

OHZ, 1-(3-Chloro-5-trifluoromethoxy-phenyl)-3-[2-(2-hydroxy-ethyl)-phenyl]-urea (C16 H14 Cl F3 N2 O3, 374.7 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5…

Component
OHZ
Formula
C16 H14 Cl F3 N2 O3
Class
ligand
Structures
4
PDB entries
2

Binding sites

OHZ in 4 structures; the first of them:

  • 6YAP · Crystal structure of ZmCKO4a in complex with inhibitor… · OHZ A604 · binds ASP170, ILE185, GLU285, VAL370, LEU377, TRP383, TRP389, ASN391 and 8 more
  • 6YAQ · Crystal sttructure of ZmCKO8 in complex with inhibitor… · OHZ A601 · binds TRP105, ASP167, ILE182, GLU281, VAL369, GLU372, LEU376, TRP382 and 9 more
  • 6YAP · Crystal structure of ZMCKO4A in complex with inhibitor 1-(3-chloro-5… · OHZ A604 · binds ASP170, ILE185, GLU285, VAL370, LEU377, TRP383, TRP389, ASN391 and 6 more
  • 6YAQ · Crystal sttructure of ZMCKO8 in complex with inhibitor 1-(3-chloro-5… · OHZ A601 · binds TRP105, ASP167, ILE182, GLU281, VAL369, GLU372, LEU376, TRP382 and 9 more

Residues it binds most

LEU 4, TRP 4, TYR 4, GLU 4, ILE 4, ASN 4, ASP 4, VAL 4, SER 2, ALA 1 (residue and the binding sites it lines).

Found with

  • FAD · Flavin-adenine dinucleotide
  • EDO · 1,2-ethanediol
  • DMS · Dimethyl sulfoxide
  • IPA · Isopropyl alcohol
  • PEG · Di(hydroxyethyl)ether

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