GL1X · GenesisL1 explorer

Ligand · OE7

OE7 · 2-({4-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)-4-chlorobenzoic acid

OE7, 2-({4-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)-4-chlorobenzoic acid (C21 H16 Cl N5 O4, 437.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every…

Component
OE7
Formula
C21 H16 Cl N5 O4
Class
ligand
Structures
2
PDB entries
2

Binding sites

OE7 in 2 structures; the first of them:

  • 6PF3 · Crystal structure of human thymidylate synthase delta (7-29) in complex with dump and… · OE7 A601 · binds PHE80, ILE108, LEU192, ASP218, LEU221, GLY222, PHE225, TYR258 and 2 more
  • 6PF8 · Crystal structure of ts-DHFR from cryptosporidium hominis in complex with NADPH, fdump… · OE7 A603 · binds LYS284, ALA287, SER290, ILE315, ASN319, LEU399, ASP426, LEU429 and 6 more

Residues it binds most

LEU 9, ALA 9, ILE 9, PHE 9, MET 9, ASP 9, GLY 9, TYR 9, ASN 5, LYS 5 (residue and the binding sites it lines).

Found with

  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
  • UFP · 5-fluoro-2'-deoxyuridine-5'-monophosphate
  • UMP · 2'-deoxyuridine 5'-monophosphate

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.