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Ligand · O6E

O6E · 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid

O6E, 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]p…

Component
O6E
Formula
C33 H38 N4 O6
Class
ligand
Structures
8
PDB entries
7

Binding sites

O6E in 8 structures; the first of them:

  • 6TC5 · Phytochromobilin-adducted PAS-GAF bidomain of Sorghum bicolor phyB · O6E AAA500 · binds TYR115, ILE119, MET289, TYR291, VAL301, TYR313, TYR318, THR321 and 20 more
  • 7RZW · CryoEM structure of Arabidopsis thaliana phytochrome B · O6E A1201 · binds TYR104, ILE108, MET274, TYR276, VAL286, TYR298, TYR303, THR306 and 24 more
  • 8F5Z · Composite map of CryoEM structure of Arabidopsis thaliana phytochrome A · O6E B1201 · binds TYR70, MET240, TYR242, TYR269, THR272, ASP273, ILE274, PRO275 and 15 more
  • 8IFF · Cryo-EM structure of Arabidopsis phytochrome A. · O6E A1201 · binds LEU71, ILE74, MET240, TYR242, TYR269, THR272, ASP273, ILE274 and 20 more
  • 8ISJ · Pr conformer of Arabidopsis thaliana phytochrome A - AtphyA-Pr · O6E A1201 · binds ILE74, MET240, TYR242, TYR269, THR272, ASP273, ILE274, PRO275 and 18 more
  • 8YB4 · Pfr conformer of Arabidopsis thaliana phytochrome B in complex with… · O6E B1201 · binds TYR83, MET274, TYR276, LEU301, TYR303, THR306, ASP307, ILE308 and 17 more
  • 9IUZ · Constitutively active mutant(Y276H) of Arabidopsis phytochrome B(phyB) in complex with… · O6E B1001 · binds HIS276, LEU301, TYR303, THR306, ASP307, ILE308, PRO309, SER312 and 16 more
  • 7RZW · Cryoem structure of arabidopsis thaliana phytochrome B · O6E A1201 · binds TYR104, ILE108, MET274, TYR276, VAL286, TYR298, TYR303, THR306 and 19 more

Residues it binds most

TYR 15, HIS 15, ARG 15, PRO 15, MET 15, ILE 15, VAL 15, SER 10, LEU 13, ALA 13 (residue and the binding sites it lines).

Found with

  • BME · Beta-mercaptoethanol

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