NGD · 3-(aminocarbonyl)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihyd roxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2- yl]pyridinium

Binding sites

NGD in 6 structures; the first of them:

• 2O3U · Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by… · NGD A301 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP155 and 9 more
• 3ZWN · Crystal structure of Aplysia cyclase complexed with substrate NGD and product cGDPR · NGD B5573 · binds PHE76, TRP77, SER78, GLY79, TYR81, LEU97, GLU98, ASN107 and 11 more
• 3ZWO · Crystal structure of ADP ribosyl cyclase complexed with reaction intermediate · NGD F5573 · binds PHE76, TRP77, SER78, GLY79, LEU97, GLU98, ASN107, TRP140 and 7 more
• 2O3U · Structural basis for formation and hydrolysis of calcium messenger cyclic ADP-ribose by… · NGD A301 · binds LEU124, TRP125, SER126, ARG127, LYS129, LEU145, GLU146, ASP155 and 9 more
• 3ZWN · Crystal structure of aplysia cyclase complexed with substrate ngd and product cgdpr · NGD B5573 · binds PHE76, TRP77, SER78, GLY79, TYR81, LEU97, GLU98, ASN107 and 11 more
• 3ZWO · Crystal structure of ADP ribosyl cyclase complexed with reaction intermediate · NGD F5573 · binds PHE76, TRP77, SER78, GLY79, LEU97, GLU98, ASN107, TRP140 and 7 more

Residues it binds most

SER 8, TRP 8, PHE 8, GLU 8, LEU 8, ARG 8, ASP 4, TYR 4, ASN 4, GLN 4 (residue and the binding sites it lines).

Found with

• CGR · Cyclic guanosine diphosphate-ribose
• G2Q · Guanosine diphosphate ribose