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Ligand · NEX

NEX · (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R, 6R)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13, 15,17-nonaenylidene}-1,5,5-trimethylcyclohexane-1,3-diol

NEX, (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R, 6R)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13, 15,17-nonaenylidene}-1,5,5-trimethylcyclohexane-1,3-diol (C40 H56 O4…

Component
NEX
Formula
C40 H56 O4
Class
ligand
Structures
32
PDB entries
29

Binding sites

NEX in 32 structures; the first of them:

  • 6IJO · Photosystem I of Chlamydomonas reinhardtii · NEX 5624 · binds ASN134, MET135, GLY136, LEU139, ILE218, VAL259, GLN260, GLY261 and 9 more
  • 6KAD · Cryo-EM structure of the C2S2M2L2-type PSII-LHCII supercomplex from Chlamydomonas… · NEX 11623 · binds TYR137, LEU159, MET160, ILE163, TYR166, PRO172, PRO188, ARG45 and 1 more
  • 7D0J · Photosystem I-LHCI-LHCII of Chlamydomonas reinhardtii · NEX P617 · binds TRP88, LEU151, LEU154, VAL155, TYR158, PRO164
  • 7DZ8 · State transition supercomplex PSI-LHCI-LHCII from the LhcbM1 lacking mutant of… · NEX 5624 · binds ASN117, MET118, GLY119, LEU122, ILE201, GLN205, VAL242, GLN243 and 9 more
  • 7E0J · LHCII-1 in the state transition supercomplex PSI-LHCI-LHCII from the double phosphatase… · NEX X1623 · binds TRP88, TYR129, VAL151, MET152, LEU154, TYR158, PRO164

Residues it binds most

TYR 185, LEU 180, PRO 136, VAL 130, TRP 133, ALA 77, MET 53, ILE 42, PHE 38, GLN 14 (residue and the binding sites it lines).

Found with

  • CLA · Chlorophyll A
  • LHG · 1,2-dipalmitoyl-phosphatidyl-glycerole
  • CHL · Chlorophyll B
  • LUT · (3R,3'R,6S)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol
  • XAT · (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-diepoxy-5,6,5',6'-tetrahydro-beta,beta-carotene-3,3'-diol
  • BCR · Beta-carotene
  • LMG · 1,2-distearoyl-monogalactosyl-diglyceride
  • DGD · Digalactosyl diacyl glycerol (dgdg)
  • PQN · Phylloquinone
  • SF4 · Iron/sulfur cluster
  • LMU · Dodecyl-alpha-D-maltoside
  • SQD · 1,2-di-O-acyl-3-O-[6-deoxy-6-sulfo-alpha-D-glucopyranosyl]-sn-glycerol

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