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Ligand · N6M

N6M · N-methyl-9H-purin-6-amine

N6M, N-methyl-9H-purin-6-amine (C6 H7 N5, 149.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
N6M
Formula
C6 H7 N5
Class
ligand
Structures
8
PDB entries
4

Binding sites

N6M in 8 structures; the first of them:

  • 2XO1 · xpt-pbuX C74U Riboswitch from B. subtilis bound to N6-methyladenine · N6M A1081 · binds A21, U22, U47, C50, U51, A52, A73, U74 and 1 more
  • 7S98 · Cryogenic Human Hsp90a-NTD bound to N6M · N6M A301 · binds ASN51, SER52, ALA55, ASP93, GLY97, MET98, LEU107, PHE138 and 1 more
  • 7S99 · Room-temperature Human Hsp90a-NTD bound to N6M · N6M A301 · binds ASN51, SER52, ALA55, ASP93, ILE96, GLY97, MET98, LEU107 and 2 more
  • 7YWB · Crystal structure of YTHDF2 in complex with N6-Methyladenine · N6M A605 · binds LYS416, SER417, TYR418, SER419, ASP422, TRP432, CYS433, SER434 and 3 more
  • 2XO1 · Xpt-pbux C74U riboswitch from B. subtilis bound to N6-methyladenine · N6M A1081 · binds A21, U22, U47, C50, U51, A52, A73, U74 and 1 more
  • 7S98 · Cryogenic human HSP90A-ntd bound to N6M · N6M A301 · binds ASN51, ALA55, ASP93, MET98, LEU107, THR184
  • 7S99 · Room-temperature human HSP90A-ntd bound to N6M · N6M A301 · binds ASN51, SER52, ALA55, ASP93, MET98, LEU107, THR184
  • 7YWB · Crystal structure of YTHDF2 in complex with N6-methyladenine · N6M A605 · binds LYS416, SER417, TYR418, ASP422, TRP432, CYS433, TRP486, TRP491 and 1 more

Residues it binds most

ASP 8, SER 7, TRP 4, U 2, A 2, ALA 4, ASN 4, CYS 4, LEU 4, LYS 4 (residue and the binding sites it lines).

Found with

  • NCO · Cobalt hexammine(iii)
  • K · Potassium ion
  • CL · Chloride ion
  • SO4 · Sulfate ion
  • ACT · Acetate ion
  • GOL · Glycerol

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