Ligand · N22
N22 · 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
N22, 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine (C17 H20 N4 O2, 312.4 g/mol), in the MolNFT structures on GenesisL1: bound in 14 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the…
- Component
- N22
- Formula
- C17 H20 N4 O2
- Class
- ligand
- Structures
- 14
- PDB entries
- 7
Binding sites
N22 in 14 structures; the first of them:
- 2KGK · Solution structure of Bacillus anthracis dihydrofolate reductase · N22 A174 · binds MET6, LEU21, PRO22, TRP23, ARG24, GLU28, LEU29, VAL32 and 4 more
- 3CSE · Candida glabrata Dihydrofolate Reductase complexed with NADPH and… · N22 A302 · binds ILE9, VAL10, ALA11, LEU25, GLU32, MET33, PHE36, THR58 and 8 more
- 3E0B · Bacillus anthracis Dihydrofolate Reductase complexed with NADPH and… · N22 A208 · binds MET6, VAL7, ALA8, ASN20, LEU21, TRP23, GLU28, LEU29 and 8 more
- 3FQ0 · Staphylococcus aureus dihydrofolate reductase complexed with NADPH and… · N22 A219 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 8 more
- 3FQO · Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and… · N22 A219 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 8 more
- 3I8A · Staphylococcus aureus H30N, F98Y Dihydrofolate Reductase complexed with NADPH and… · N22 X219 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 9 more
- 3QLW · Candida albicans dihydrofolate reductase complexed with NADPH and… · N22 A194 · binds ILE9, VAL10, ALA11, MET25, GLU32, ILE33, PHE36, THR58 and 7 more
- 2KGK · Solution structure of bacillus anthracis dihydrofolate reductase · N22 A174 · binds MET6, LEU21, PRO22, TRP23, ARG24, GLU28, LEU29, VAL32 and 4 more
- 3CSE · Candida glabrata dihydrofolate reductase complexed with NADPH and 2,4… · N22 A302 · binds ILE9, VAL10, ALA11, LEU25, GLU32, MET33, PHE36, THR58 and 8 more
- 3E0B · Bacillus anthracis dihydrofolate reductase complexed with NADPH and 2… · N22 A208 · binds MET6, VAL7, ALA8, ASN20, LEU21, TRP23, GLU28, LEU29 and 8 more
- 3FQ0 · Staphylococcus aureus dihydrofolate reductase complexed with NADPH and… · N22 A219 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 8 more
- 3FQO · Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and… · N22 A219 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 8 more
- 3I8A · Staphylococcus aureus H30N, F98Y dihydrofolate reductase complexed with NADPH and… · N22 X219 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 9 more
- 3QLW · Candida albicans dihydrofolate reductase complexed with NADPH and 5… · N22 A194 · binds ILE9, VAL10, ALA11, MET25, GLU32, ILE33, PHE36, THR58 and 7 more
Residues it binds most
LEU 20, ILE 20, THR 18, VAL 20, PHE 20, ALA 18, ASN 10, TYR 16, GLU 14, MET 14 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.