Ligand · MZQ
MZQ · 7-[2,4-bis(fluoranyl)phenyl]-3-[(3~{R})-1-propanoylpyrrolidin-3-yl]-4~{H}-isoquinolin-1-one
MZQ, 7-[2,4-bis(fluoranyl)phenyl]-3-[(3~{R})-1-propanoylpyrrolidin-3-yl]-4~{H}-isoquinolin-1-one (C22 H20 F2 N2 O2, 382.4 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues…
- Component
- MZQ
- Formula
- C22 H20 F2 N2 O2
- Class
- ligand
- Structures
- 1
- PDB entries
- 1
Binding sites
MZQ in 1 structure; the first of them:
- 6TAM · X-ray structure of human K-RAS G12C in complex with covalent isoquinolinone inhibitor… · MZQ A203 · binds VAL9, GLY10, CYS12, GLY13, LYS16, PRO34, THR58, ALA59 and 9 more
Residues it binds most
GLY 1, GLN 1, VAL 1, ALA 1, ARG 1, CYS 1, GLU 1, ILE 1, LYS 1, MET 1 (residue and the binding sites it lines).
Found with
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