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Ligand · MZE

MZE · 1-~{tert}-butyl-3-[1-[(2~{S})-3-(3-carbamimidoylphenyl)-2-[[3-(3-carbamimidoylphenyl) phenyl]sulfonylamino]propanoyl]piperidin-4-yl]urea

MZE, 1-~{tert}-butyl-3-[1-[(2~{S})-3-(3-carbamimidoylphenyl)-2-[[3-(3-carbamimidoylphenyl) phenyl]sulfonylamino]propanoyl]piperidin-4-yl]urea (C33 H42 N8 O4 S, 646.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
MZE
Formula
C33 H42 N8 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

MZE in 2 structures; the first of them:

  • 6T9U · Bovine Trypsine in complex with the synthetic inhibitor… · MZE A302 · binds HIS57, ASN97, THR98, LEU99, GLN175, ASP189, SER190, CYS191 and 11 more
  • 6T9U · Bovine trypsine in complex with the synthetic inhibitor (S)-3'-(N-(1… · MZE A302 · binds HIS57, ASN97, THR98, LEU99, GLN175, ASP189, SER190, CYS191 and 10 more

Residues it binds most

SER 2, GLY 2, CYS 2, GLN 2, ASN 2, ASP 2, HIS 2, LEU 2, THR 2, TRP 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • DMS · Dimethyl sulfoxide
  • TFA · trifluoroacetic acid

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