Ligand · MOA

MOA · Mycophenolic acid

MOA, Mycophenolic acid (C17 H20 O6, 320.3 g/mol), in the MolNFT structures on GenesisL1: bound in 17 records (9 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component: MOA
Formula: C17 H20 O6
Class: ligand
Structures: 17
PDB entries: 9

Binding sites

MOA in 17 structures; the first of them:

1JR1 · Crystal structure of Inosine Monophosphate Dehydrogenase in complex with Mycophenolic Acid · MOA A1332 · binds ASP274, SER275, SER276, ASN303, ARG322, GLY324, MET325, GLY326 and 5 more
1ME7 · Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP and MOA… · MOA A600 · binds ASP261, SER262, SER263, ASN291, LYS310, GLY312, ILE313, GLY314 and 5 more
1MEH · Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP and MOA… · MOA A600 · binds ASP261, SER262, SER263, ASN291, LYS310, GLY312, ILE313, GLY314 and 6 more
1MEI · Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and… · MOA A600 · binds ASP261, SER262, SER263, ASN291, LYS310, GLY312, ILE313, GLY314 and 6 more
4AF0 · Crystal structure of cryptococcal inosine monophosphate dehydrogenase · MOA A1526 · binds ASP288, SER289, SER290, ASN317, ARG336, GLY338, MET339, GLY340 and 5 more
4FO4 · Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, complexed… · MOA A502 · binds ASP250, SER251, SER252, ASN279, LYS298, GLY300, ILE301, GLY302 and 6 more
4FXS · Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae complexed with IMP and… · MOA A702 · binds ASP250, SER251, SER252, ASN279, LYS298, GLY300, ILE301, GLY302 and 6 more
7DBL · Acyl-CoA hydrolase MpaH' mutant S139A in complex with MPA · MOA A501 · binds GLY59, VAL60, LEU62, TRP111, ALA139, PHE140, LEU165, GLN167 and 11 more
7WKZ · Crystal structure of the HSA complex with mycophenolate and aripiprazole · MOA A602 · binds TYR150, LYS195, LEU198, LYS199, SER202, PHE211, TRP214, ALA215 and 7 more
1JR1 · Crystal structure of inosine monophosphate dehydrogenase in complex with mycophenolic acid · MOA A1332 · binds ASP274, SER275, SER276, ASN303, ARG322, GLY324, MET325, GLY326 and 5 more
1ME7 · Inosine monophosphate dehydrogenase (impdh) from tritrichomonas foetus with rvp and moa… · MOA A600 · binds ASP261, SER262, SER263, ASN291, LYS310, GLY312, ILE313, GLY314 and 5 more
1MEH · Inosine monophosphate dehydrogenase (impdh) from tritrichomonas foetus with imp and moa… · MOA A600 · binds ASP261, SER262, SER263, ASN291, LYS310, GLY312, ILE313, GLY314 and 6 more
1MEI · Inosine monophosphate dehydrogenase (impdh) from tritrichomonas foetus with xmp and… · MOA A600 · binds ASP261, SER262, SER263, ASN291, LYS310, GLY312, ILE313, GLY314 and 6 more
4AF0 · Crystal structure of cryptococcal inosine monophosphate dehydrogenase · MOA A1526 · binds ASP288, SER289, SER290, ASN317, ARG336, GLY338, MET339, GLY340 and 5 more
4FO4 · Inosine 5'-monophosphate dehydrogenase from vibrio cholerae, deletion mutant, complexed… · MOA A502 · binds ASP250, SER251, SER252, ASN279, LYS298, GLY300, ILE301, GLY302 and 6 more
4FXS · Inosine 5'-monophosphate dehydrogenase from vibrio cholerae complexed with imp and… · MOA A702 · binds ASP250, SER251, SER252, ASN279, LYS298, GLY300, ILE301, GLY302 and 6 more
7DBL · Acyl-CoA hydrolase mpah' mutant S139A in complex with mpa · MOA A501 · binds GLY59, VAL60, LEU62, TRP111, ALA139, PHE140, LEU165, GLN167 and 11 more

Residues it binds most

GLY 28, SER 30, ASP 20, ARG 22, LEU 10, GLN 16, MET 12, PRO 8, ASN 20, ILE 20 (residue and the binding sites it lines).

Found with

K · Potassium ion
IMP · Inosinic acid
RVP · Ribavirin monophosphate
XMP · Xanthosine-5'-monophosphate
NA · Sodium ion
SO4 · Sulfate ion
9SC · 7-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one

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