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Ligand · MED

MED · D-methionine

MED, D-methionine (C5 H11 N O2 S, 149.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
MED
Formula
C5 H11 N O2 S
Class
ligand
Structures
6
PDB entries
6

Binding sites

MED in 6 structures; the first of them:

  • 1KQ0 · Human methionine aminopeptidase type II in complex with D-methionine · MED A601 · binds PHE219, PRO220, HIS231, ASP251, ASP262, HIS331, ILE338, HIS339 and 3 more
  • 1TKJ · Streptomyces griseus aminopeptidase complexed with D-Methionine · MED A913 · binds HIS85, ASP97, GLU131, GLU132, ASP160, MET161, TYR172, GLY199 and 5 more
  • 1Y9Q · Crystal Structure of HTH_3 family Transcriptional Regulator from Vibrio cholerae · MED A201 · binds ILE53, TRP57, MSE90, ILE92, PHE107, ILE109, SER119, HIS122 and 5 more
  • 6DZX · Crystal structure of the N. meningitides methionine-binding protein in its D-methionine… · MED A1001 · binds PHE54, TYR81, PHE98, GLN99, HIS100, TYR103, THR123, ASN153 and 6 more
  • 6WKB · Human S-adenosylmethionine synthetase co-crystallized with UppNHp and Met · MED A402 · binds ALA55, GLU70, GLN113, ILE117, GLY133, ASP134, LYS289, GLY257 and 1 more
  • 7UO8 · Co-crystal structure of Salmonella Typhimurium Tlde1a in complex with D-methionine · MED A701 · binds PRO39, ASP40, LYS114, ARG115, GLY116, PHE118, HIS129, GLY130 and 3 more

Residues it binds most

ASN 7, TYR 8, HIS 10, PHE 10, GLY 8, ARG 8, ASP 4, GLN 7, ALA 6, THR 6 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • MET · Methionine
  • U4P · 5'-deoxyuridine
  • CA · Calcium ion
  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol
  • TBU · Tertiary-butyl alcohol

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