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Ligand · LTB

LTB · Leukotriene B4

LTB, Leukotriene B4 (C20 H32 O4, 336.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
LTB
Formula
C20 H32 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

LTB in 2 structures; the first of them:

  • 7VKT · cryo-EM structure of LTB4-bound BLT1 in complex with Gi protein · LTB A401 · binds ALA21, PHE74, PHE77, LEU78, GLY98, MET101, TYR102, VAL105 and 7 more
  • 7VKT · Cryo-EM structure of LTB4-bound BLT1 in complex with gi protein · LTB A401 · binds PHE74, PHE77, LEU78, GLY98, MET101, TYR102, VAL105, VAL152 and 5 more

Residues it binds most

PHE 2, VAL 2, GLY 2, ASN 2, GLU 2, ILE 2, LEU 2, MET 2, TRP 2, TYR 2 (residue and the binding sites it lines).

Found with

  • 8IO · [(2R)-2-[(Z)-hexadec-9-enoyl]oxy-3-[oxidanyl-[(2S,3R, 5R,6S)-2,3,4,5,6-pentakis(oxidanyl)cyclohexyl]oxy-phosphoryl]oxy-propyl] octadecanoate
  • Y01 · Cholesterol hemisuccinate

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