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Ligand · LOG

LOG · N-acetylglucosaminono-1,5-lactone (Z)-oxime

LOG, N-acetylglucosaminono-1,5-lactone (Z)-oxime (C8 H14 N2 O6, 234.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
LOG
Formula
C8 H14 N2 O6
Class
sugar
Structures
8
PDB entries
4

Binding sites

LOG in 8 structures; the first of them:

  • 2XM2 · BtGH84 in complex with LOGNAc · LOG A1000 · binds GLY135, PHE136, TYR137, LYS166, ASP242, ASP243, CYS278, TYR282 and 11 more
  • 4AZ7 · Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal… · LOG A1614 · binds ARG196, ASN225, HIS297, ASP360, GLU361, PHE415, TRP439, TYR469 and 4 more
  • 4AZH · Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal… · LOG A2044 · binds ARG641, ASN670, HIS742, ASP804, GLU805, PHE849, TRP872, TYR902 and 3 more
  • 5BXP · LNBase in complex with LNB-LOGNAc · LOG C1 · binds HIS263, ASP320, GLU321, TRP373, TRP394, TYR419, TYR427, TRP465 and 1 more
  • 2XM2 · BTGH84 in complex with lognac · LOG A1000 · binds GLY135, PHE136, TYR137, LYS166, ASP242, ASP243, CYS278, TYR282 and 11 more
  • 4AZ7 · Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal… · LOG A1614 · binds ARG196, ASN225, HIS297, ASP360, GLU361, PHE415, TRP439, TYR469 and 4 more
  • 4AZH · Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal… · LOG A2044 · binds ARG641, ASN670, HIS742, ASP804, GLU805, PHE849, TRP872, TYR902 and 3 more
  • 5BXP · Lnbase in complex with lnb-lognac · LOG C1 · binds HIS263, ASP320, GLU321, TRP373, TRP394, TYR419, TYR427, TRP465 and 1 more

Residues it binds most

ASP 20, TRP 18, TYR 20, ASN 14, HIS 16, GLU 14, PHE 14, ILE 12, ARG 10, VAL 6 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • P15 · 2,5,8,11,14,17-hexaoxanonadecan-19-ol
  • MG · Magnesium ion
  • GAL · beta-D-galactopyranose
  • SO4 · Sulfate ion
  • GOL · Glycerol

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